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Confocal images were acquired with a Zeiss inverted LSM 789 laser scanning confocal microscope (Zeiss) using a 100x/1.4 DIC Plan-Apochromat oil immersion objective

Histamine intolerance and MCAS are often underdiagnosed, and the exact prevalence of these conditions is not fully established

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5 New strategies for drug development The emergence of resistance from the prolonged or monotherapeutic use of traditional antifungal agents, combined with the low success rate of new drug development, continues to hinder effective treatment of clinical fungal infections